Does gut microbiota play a role in the loss of intake control in obesity?

Rafael Maldonado

  • PROJECT LEADER

    Rafael Maldonado

  • HOST ORGANIZATION,
    COUNTRY

    NeuroPhar-MELIS, Universitat Pompeu Fabra (UPF), Spain

  • DESCRIPTION

    At present, four in ten people in the world are overweight or obese, and the incidence of these two conditions is increasing, particularly in developed countries, where they are reaching alarming levels and represent a serious public health problem.

    These metabolic pathologies are often associated with complex alterations that lead to a loss of behavioural control that promotes weight gain. In this project, the researchers will study which environmental factors impact on brain function and lead to loss of appetite control. More specifically, they will focus on epigenetic mechanisms mediated by the gut microbiota.

    The project results will generate greater understanding of these diseases and the role that behaviour plays, and will identify new biomarkers to identify the individuals that are most at risk of losing appetite control, as well as opening the door to the development of new therapies to treat obesity and overweight, and eating disorders.

  • PARTNER ORGANIZATIONS

    • Raul Andero Galí, Institute of Neuroscience, Universitat Autònoma de Barcelona (UAB), Spain

    • José Manuel Fernández-Real, Institut d'Investigació Biomèdica de Girona, Universitat de Girona, Spain

  • PROJECT TITLE

    Involvement of the gut microbiota-brain cross talk in the loss of eating control

  • BUDGET

    €999,948.94